http://pubs.acs.org/doi/abs/10.1021/...rchHistoryKey=Here, we demonstrate that the active component of marijuana, Δ9-tetrahydrocannabinol (THC), competitively inhibits the enzyme acetylcholinesterase (AChE) as well as prevents AChE-induced amyloid β-peptide (Aβ) aggregation, the key pathological marker of Alzheimer's disease. Computational modeling of the THC−AChE interaction revealed that THC binds in the peripheral anionic site of AChE, the critical region involved in amyloidgenesis. Compared to currently approved drugs prescribed for the treatment of Alzheimer's disease, THC is a considerably superior inhibitor of Aβ aggregation, and this study provides a previously unrecognized molecular mechanism through which cannabinoid molecules may directly impact the progression of this debilitating disease.
If there was a tile for worst forum moderator ever, Gonzo would win. Doesn't even know what the word hypocrite means.
Amusingly, i too came in here to mention a mod
Big fan of the emotional breakdown Sycophant7 is having on the main board. Big fan. Not even going to go into the reasons why, not going to break it down, the evidence is there for all to see. Just a big fan of how emotionally wounded youve become by a bad report. Absolutely hilarious.
The only thing im somewhat annoyed about it how this has completely overshadowed our last win. Players quitting football is relatively rare enough that i expected some media coverage on it. But how horrifically this has been handled(by Martin, the other players, the team, even the union a bit) has totally covered up a win for us. In an ideal world Martin would just come out and clear the air. Clearly thats not going to happen, thus people are left digging. And like with most things, people dig up the wrong information, rely on the wrong source, or make connections that just arent there. The next week is going to be fun.
Was expecting a Skeptical Walrus reply to my "cannabis cures alzheimers" post.